Description

Midazolam 7.5mg is a potent benzodiazepine medication commonly prescribed for short-term relief of acute anxiety, insomnia, and to induce sedation prior to surgeries or diagnostic procedures. Each tablet contains 7.5mg of midazolam, offering rapid calming effects by acting on the brain’s GABA receptors.https://relaxmeds.shop/

This medication is ideal for individuals suffering from severe anxiety episodes or those needing pre-medication to relax before undergoing stressful medical treatments. Due to its quick onset and short duration, it is highly effective for temporary but intense anxiety-related conditions.

Key Benefits:

• Fast-acting relief from acute anxiety

• Commonly used before surgeries or dental procedures

• Helps induce relaxation and sleep

• Short half-life for controlled sedation

Dosage & Usage: Typically taken orally 30–60 minutes before a procedure or as prescribed for anxiety or sleep issues. Do not mix with alcohol or other sedatives. Not suitable for long-term use.

Warning: Midazolam is a controlled substance and may cause dependency. Use under strict medical supervision. Avoid driving or operating machinery after use.

Note: Adult use only. Not recommended during pregnancy or for individuals with respiratory issues.

Indications and Uses:

Midazolam 7.5 mg is typically prescribed for:

• Preoperative sedation and anxiolysis (to reduce anxiety and induce relaxation before medical procedures)

• Short-term treatment of severe insomnia

• Adjunct to anesthesia

• Status epilepticus (more commonly in injectable form)

• Severe anxiety disorders, although long-term use is generally discouraged due to dependency risk

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Pharmacokinetics:

• Absorption: Rapidly absorbed after oral administration; peak plasma concentration reached in about 30–60 minutes.

• Half-life: Approximately 1.5–2.5 hours in healthy adults; may be prolonged in elderly or those with liver impairment.

• Metabolism: Hepatically metabolized, primarily by cytochrome P450 3A4 (CYP3A4).

• Excretion: Renally, mostly as inactive metabolites.https://relaxmeds.shop/

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Side Effects:

Common side effects include:

• Drowsiness

• Dizziness

• Decreased alertness

• Fatigue

• Memory impairment (anterograde amnesia)

• Impaired coordination

Serious side effects (rare but may occur):

• Respiratory depression (especially when combined with opioids or alcohol)

• Hypotension

• Paradoxical reactions (e.g., agitation, aggression)

• Dependence and withdrawal symptoms with long-term use

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Contraindications:

• Known hypersensitivity to midazolam or other benzodiazepines

• Severe respiratory insufficiency (unless mechanically ventilated)

• Myasthenia gravis

• Acute narrow-angle glaucoma

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Cautions and Warnings:

• Use with caution in elderly patients, those with hepatic or renal impairment, and those with a history of substance abuse.

• Avoid alcohol and CNS depressants during use.

• Risk of dependence and withdrawal symptoms with prolonged use.

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Pregnancy and Lactation:

• Pregnancy Category D (in many jurisdictions): May cause fetal harm; should only be used if clearly needed.

• Midazolam is excreted in breast milk; use with caution during breastfeeding.

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Drug Interactions:

• Increased sedation with opioids, alcohol, antipsychotics, antihistamines, and other CNS depressants

• CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) can increase midazolam levels

• CYP3A4 inducers (e.g., rifampin, carbamazepine) can decrease its effect https://www.mayoclinic.org/drugs-supplements/midazolam-oral-route/description/drg-20072182

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Storage:

• Store at room temperature (20°C to 25°C or 68°F to 77°F)

• Protect from moisture and light

• Keep out of reach of children.https://relaxmeds.shop/